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Jose de Leon Selected Research

Seizures (Absence Seizure)

4/2024Optimizing co-prescription of clozapine and antiseizure medications: a systematic review and expert recommendations for clinical practice.
9/2023The introduction of clozapine at the Nathan Kline Institute in New York and its long-term consequences.
1/2023Optimization of Therapy in Patients with Epilepsy and Psychiatric Comorbidities: Key Points.

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Jose de Leon Research Topics

Disease

25Drug-Related Side Effects and Adverse Reactions
04/2024 - 08/2003
24Schizophrenia (Dementia Praecox)
09/2023 - 01/2004
20Myocarditis (Carditis)
04/2024 - 01/2016
18Inflammation (Inflammations)
03/2024 - 09/2017
17Obesity
11/2023 - 02/2005
15Pneumonia (Pneumonitis)
04/2024 - 11/2017
14Infections
10/2022 - 09/2003
9Mental Disorders (Mental Disorder)
11/2023 - 06/2005
8Agranulocytosis (Granulocytopenia)
04/2024 - 01/2019
8Bipolar Disorder (Manic Depressive Psychosis)
01/2023 - 05/2007
8Weight Gain
10/2018 - 09/2006
7Psychotic Disorders (Schizoaffective Disorder)
11/2023 - 08/2004
7Fever (Fevers)
09/2023 - 09/2003
6Metabolic Syndrome (Dysmetabolic Syndrome X)
03/2012 - 05/2007
6Hyperlipidemias (Hyperlipidemia)
09/2011 - 05/2007
6Tobacco Use Disorder (Nicotine Dependence)
09/2006 - 09/2002
5Tardive Dyskinesia
09/2023 - 10/2005
5Treatment-Resistant Schizophrenia
01/2022 - 02/2007
4Hypersensitivity (Allergy)
04/2024 - 01/2022
4Intellectual Disability (Idiocy)
11/2023 - 07/2009
4COVID-19
11/2022 - 01/2020
4Catatonia
05/2019 - 01/2017
4Body Weight (Weight, Body)
10/2018 - 03/2012
4Hypertension (High Blood Pressure)
03/2012 - 09/2006
3Seizures (Absence Seizure)
04/2024 - 01/2023
3Pancreatitis
11/2023 - 01/2019
3Constipation
11/2023 - 08/2003
3Obsessive-Compulsive Disorder (Disorder, Obsessive-Compulsive)
01/2019 - 01/2013
3Hypercholesterolemia
03/2012 - 01/2008
3Hypertriglyceridemia
12/2009 - 09/2006
3Substance-Related Disorders (Drug Abuse)
04/2008 - 07/2002
2Neutropenia
04/2024 - 03/2023
2Cardiac Arrhythmias (Arrythmia)
11/2023 - 01/2010
2Movement Disorders (Movement Disorder)
09/2023 - 01/2019
2Respiratory Aspiration
02/2023 - 09/2022
2Hepatitis
10/2022 - 01/2019
2Neoplasms (Cancer)
01/2022 - 01/2021
2Hemorrhage
01/2020 - 03/2012
2Attention Deficit Disorder with Hyperactivity (Attention Deficit Hyperactivity Disorder)
12/2019 - 01/2019
2Mania (Manias)
12/2018 - 05/2015
2Myoclonus (Nocturnal Myoclonus)
01/2018 - 09/2003
2Pain (Aches)
01/2018 - 01/2015
2Nausea
03/2016 - 10/2015
2Torsades de Pointes (Torsade de Pointes)
01/2016 - 05/2014
2Respiratory Tract Infections (Respiratory Tract Infection)
08/2004 - 09/2003
1Cardiac Sudden Death (Sudden Cardiac Arrest)
11/2023
1Pericardial Effusion
11/2023
1Nervous System Diseases (Neurological Disorders)
11/2023
1Syncope (Fainting)
11/2023
1Pericarditis
11/2023
1Enuresis
10/2023
1Sialorrhea
10/2023
1Substance Withdrawal Syndrome (Withdrawal Symptoms)
09/2023
1Epilepsy (Aura)
01/2023

Drug/Important Bio-Agent (IBA)

67Clozapine (Clozaril)FDA LinkGeneric
04/2024 - 02/2003
37Antipsychotic Agents (Antipsychotics)IBA
09/2023 - 07/2002
12Olanzapine (Zyprexa)FDA Link
01/2022 - 08/2004
10Valproic Acid (Depakote)FDA LinkGeneric
01/2023 - 06/2009
6Antidepressive Agents (Antidepressants)IBA
10/2023 - 12/2002
6Quetiapine Fumarate (Seroquel)FDA Link
01/2022 - 05/2007
5Lamotrigine (Lamictal)FDA LinkGeneric
04/2024 - 05/2007
5Risperidone (Risperdal Consta)FDA LinkGeneric
09/2017 - 01/2005
5Triglycerides (Triacylglycerol)IBA
10/2015 - 05/2007
5ORALIT (ORS)IBA
09/2015 - 02/2005
5Cytochrome P-450 CYP2D6 (CYP2D6)IBA
01/2010 - 08/2003
4Carbamazepine (Tegretol)FDA LinkGeneric
04/2024 - 05/2007
4Topiramate (Topamax)FDA LinkGeneric
04/2024 - 03/2012
4C-Reactive ProteinIBA
03/2024 - 01/2020
4Fluvoxamine (Luvox)FDA LinkGeneric
11/2023 - 01/2020
4Oral ContraceptivesIBA
03/2022 - 01/2020
4Glucose (Dextrose)FDA LinkGeneric
10/2015 - 05/2007
3BenzodiazepinesIBA
09/2022 - 12/2002
3Serotonin (5 Hydroxytryptamine)IBA
01/2020 - 12/2009
3Oxcarbazepine (Trileptal)FDA LinkGeneric
05/2019 - 05/2007
3Caffeine (No Doz)FDA LinkGeneric
05/2015 - 01/2004
3ziprasidone (Geodon)FDA Link
01/2014 - 09/2006
3HDL CholesterolIBA
03/2012 - 05/2007
3LipidsIBA
03/2012 - 05/2007
2Tricyclic Antidepressive Agents (Tricyclic Antidepressants)IBA
01/2023 - 12/2002
2Anticonvulsants (Antiepileptic Drugs)IBA
09/2022 - 05/2017
2Cytochrome P-450 Enzyme System (Cytochrome P450)IBA
01/2020 - 10/2005
2Aripiprazole (Abilify)FDA Link
12/2016 - 07/2009
2Metformin (Glucophage)FDA LinkGeneric
03/2016 - 10/2015
2Haloperidol (Haldol)FDA LinkGeneric
01/2016 - 09/2011
2CholesterolIBA
10/2015 - 05/2007
2Insulin (Novolin)FDA Link
10/2015 - 03/2012
2Selective Serotonin Reuptake Inhibitors (Serotonin Reuptake Inhibitors)IBA
05/2014 - 01/2013
2Chlorpromazine (Thorazine)FDA Link
12/2009 - 01/2008
2Acetyl-CoA CarboxylaseIBA
12/2009 - 01/2008
2Neuropeptide YIBA
12/2009 - 01/2008
2norclozapineIBA
02/2007 - 09/2003
2SmokeIBA
09/2006 - 09/2002
1LithiumIBA
03/2023
1perampanelIBA
01/2023
1Maprotiline (Ludiomil)FDA Link
01/2023
1Levetiracetam (Keppra)FDA LinkGeneric
01/2023

Therapy/Procedure

6Therapeutics
02/2023 - 09/2006
4Polypharmacy
09/2022 - 01/2010
3Duration of Therapy
12/2009 - 02/2005
2Self Medication
09/2006 - 03/2005